(generic: Clomipramine)

Clomipramine is in a class of drugs called tricyclic antidepressants. It affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive disorder. Clomipramine is used to relieve symptoms of obsessive-compulsive disorder such as recurrent thoughts or feelings and repetitive actions.


What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.


What happens if I overdose?

Seek emergency medical attention.
Symptoms of a clomipramine overdose include seizures, confusion, drowsiness, agitation, hallucinations, and low blood pressure (dizziness, fatigue, fainting).


Possible side effects of Clomipramine

If you experience any of the following serious side effects, stop taking clomipramine and contact your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; hives);

  • seizures;

  • a fast or irregular heartbeat;

  • a heart attack;

  • high blood pressure (blurred vision, severe headache);

  • difficulty urinating; or

  • fever with increased sweating, muscle stiffness, or severe muscle weakness.


Other, less serious side effects may be more likely to occur. Continue to take clomipramine and talk to your doctor if you experience

  • drowsiness or dizziness;

  • dry mouth and eyes;

  • constipation;

  • mild tremor;

  • sweating;

  • mild agitation, weakness, or headache;

  • ringing in the ears;

  • nausea; or

  • loss of weight or appetite.


Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.



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