Elavil®, Endep®, Vanatrip® ...and more
(generic: Amitriptyline)

Amitriptyline is in a class of drugs called tricyclic antidepressants. Amitriptyline affects chemicals in the brain that may become unbalanced and cause depression.
Amitriptyline is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide. Amitriptyline is also sometimes used to treat certain types of pain.


What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.


What happens if I overdose?

Seek emergency medical attention.
Symptoms of an amitriptyline overdose include seizures, confusion, drowsiness, agitation, hallucinations, and low blood pressure (dizziness, fatigue, fainting).


Possible side effects of Amitriptyline

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives);

  • seizures;

  • a fast or irregular heartbeat;

  • a heart attack;

  • high blood pressure (blurred vision, headache);

  • difficulty urinating; or

  • fever with increased sweating, muscle stiffness, or severe muscle weakness.


Other, less serious side effects may be more likely to occur. Continue to take amitriptyline and talk to your doctor if you experience

  • drowsiness or dizziness;

  • dry mouth and eyes;

  • constipation;

  • mild tremor;

  • sweating;

  • mild agitation, weakness, or headache;

  • ringing in the ears;

  • nausea; or

  • loss of weight or appetite.



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